Sonazoid CEUS for Early HCC Surveillance
NCT07590284 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 556
Last updated 2026-05-15
Summary
This study is a multicenter, prospective study. In this study, enrolled subjects are cirrhotic patients of any etiology. The US and Sonazoid CEUS monitoring strategy was performed for cirrhotic patients: US and AFP joint with Sonazoid CEUS every 4 to 6 months, and combined CECT/CEMRI every 12 months.
Conditions
- Liver Cirrhosis
- Liver Fibrosis
Interventions
- DIAGNOSTIC_TEST
-
Sonazoid CEUS
Sonazoid CEUS examination
Sponsors & Collaborators
-
Tianjin Third Central Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-30
- Primary Completion
- 2029-12-30
- Completion
- 2029-12-30
Countries
- China
Study Locations
More Related Trials
-
Diagnosis of Nodules ≤2 cm Based on US and CEUS Compared With Current Clinical Procedure
NCT05360420 ·Status: UNKNOWN ·Phase: NA
-
A Novel Imaging Based Quantitative Model-aided Detection of Portal Hypertension in Patients With Cirrhosis (CHESS2104)
NCT05068492 ·Status: NOT_YET_RECRUITING
-
Comparison of Biannual Ultrasonography and Annual Unenhanced Magnetic Resonance Imaging for HCC Surveillance
NCT02854241 ·Status: UNKNOWN ·Phase: NA
-
Role of CEUS as a Secondary Diagnostic Modality
NCT04494022 ·Status: UNKNOWN ·Phase: NA
-
An Observational Study To Assess Liver Fibrosis Stages in Patients With Chronic Hepatitis C Infection
NCT01671046 ·Status: COMPLETED
-
Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
NCT03405909 ·Status: COMPLETED
-
A Novel Spleen-dedicated Stiffness Measured by FibroScan to Evaluate Cirrhotic Portal Hypertension (CHESS2105)
NCT05052892 ·Status: UNKNOWN
-
HCC Surveillance: Comparison of Abbreviated Non-contrast MRI and Ultrasound Surveillance in Cirrhotic Patients With Suboptimal Ultrasound Visualisation
NCT04455932 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Proteome Multimarker Panel With Multiple Reaction Monitoring as a Surveillance for Hepatocellular Carcinoma
NCT05756699 ·Status: ACTIVE_NOT_RECRUITING
-
Microbiome/Peptidome-based Model for Non-invasive Detection of High-risk Gastroesophageal Varices in Compensated Cirrhosis (CHESS1901/APPHA1901)
NCT03990753 ·Status: UNKNOWN
-
Annual MRI Versus Biannual US for Surveillance of Hepatocellular Carcinoma in Liver Cirrhosis
NCT02551250 ·Status: COMPLETED
-
An AI Model Based on Smartphone-derived Multimodality Images to Evaluate Portal Hypertension in Patients With Cirrhosis (CHESS2203)
NCT05402410 ·Status: UNKNOWN
-
An Efficacy and Safety Study of Sonazoid™ and SonoVue® in Participants With Focal Liver Lesions, Undergoing Pre- and Post-Contrast Ultrasound Imaging
NCT03335566 ·Status: COMPLETED ·Phase: PHASE3
-
Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver Disease
NCT03635541 ·Status: UNKNOWN
-
Non-invasive Prediction of Esophageal Varices in Liver Cirrhosis: A Multicenter Observational Study
NCT02593799 ·Status: COMPLETED
-
A Study to Evaluate Liver Stiffness With Shear Wave Elastography
NCT05097963 ·Status: COMPLETED ·Phase: NA
-
EUS Elastography for Predicting Cirrhotic-related Complications
NCT04155398 ·Status: ACTIVE_NOT_RECRUITING
-
Assessment of Liver Fibrosis and Prognosis in Chinese Patients With CHB Infection Using STE/STQ Elastography
NCT03530657 ·Status: UNKNOWN
-
Non-invasive Diagnosis of Portal Hypertension in Cirrhosis Based on Metabolomics Technology
NCT05551884 ·Status: UNKNOWN
-
Contrast Enhanced (CE) Ultrasound and CE Computed Tomography or CE Magnetic Resonance Imaging in Liver Masses
NCT00828607 ·Status: COMPLETED
-
Multicenter Clinical Study on Noninvasive Assessment of Hepatic Steatosis and Fibrosis Using Visual Transient Elastography
NCT07128108 ·Status: RECRUITING
-
Point-of-care Ultrasound Screening and Assessment of Chronic Liver Diseases and NASH
NCT05120557 ·Status: UNKNOWN ·Phase: NA
-
Biannual Screening for HCC Offered to Patients With Cirrhosis. Introducing Surveillance for Hepatocellular Carcinoma (HCC) in the Central Denmark Region Using Ultrasound and Alpha-Fetoprotein to Reduce HCC-Related Mortality in Patients With Compensated Non-Viral Cirrhosis
NCT07469319 ·Status: RECRUITING ·Phase: NA
-
Application Value of CEUS Li-RADS in Hepatic Focal Lesions in Patients With Non-high Risk Factors for HCC
NCT04920214 ·Status: UNKNOWN
-
ShearWave™ Elastography to Assess Liver Fibrosis in Chinese Patients With Hepatitis B
NCT02313649 ·Status: COMPLETED