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Evaluation of Fluid Biomarkers Around Implants Exhibiting Early Stage Periimplant Bone Loss

NCT07584759 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 59

Last updated 2026-05-13

No results posted yet for this study

Summary

This study aimed to compare biological mediators known to be important in peri-implant diseases in implants with and without early stage marginal bone loss. A total of 118 implants in 59 patients were designated as test and control groups. The radiographic and periodontal data of the included implants, along with peri-implant sulcus fluid samples, were evaluated.

Conditions

  • Peri-implant Bone Loss
  • Peri-implant Marginal Bone Loss
  • Marginal Bone Loss
  • Peri-Implant Health

Interventions

OTHER

Collecting of peri-implant sulcus fluid

To evaluate biomarkers associated with peri-implant bone loss, periopaper was placed in the peri-implant pocket and absorbed with sulcus fluid.

DIAGNOSTIC_TEST

Periapical radiography

Parallel cone technique was used during periapical imaging to accurately measure peri-implant bone loss.

Sponsors & Collaborators

  • Pamukkale University scientific research project department

    collaborator UNKNOWN

  • Pamukkale University

    lead OTHER

Principal Investigators

  • Raziye Tugce Can Keles, R.A. · Pamukkale University Faculty of Dentistry, Department of Periodontology

  • Gizem Torumtay Cin, Assoc. Prof. · Pamukkale University Faculty of Dentistry, Department of Periodontology

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-03-06
Primary Completion
2025-09-06
Completion
2025-09-06

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07584759 on ClinicalTrials.gov