Engagement Study for Participants With Factor V Leiden and Prothrombin G20210A Mutations
NCT07584265 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2026-05-29
Summary
This study will enrol individuals who have, or may have, Factor V Leiden or Prothrombin G20210A mutations, which are genetic changes linked to an increased risk of blood clots. Targeted genetic testing will be carried out, where appropriate, to confirm whether participants have one of these genetic variants. Those with a confirmed result will attend a site visit for basic health checks, including blood pressure measurements, ECG, and blood tests, to establish a baseline of their general health and help identify suitability for future related clinical trials.
The study also provides participants with the opportunity to learn more about clinical research and become familiar with the clinical trial unit and team. Participation lasts approximately 10 weeks and includes 1-2 site visits and a follow-up telephone call.
Conditions
- Factor V Leiden
- Prothrombin G20210A
Sponsors & Collaborators
-
Richmond Research Institute
lead INDUSTRY
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-21
- Primary Completion
- 2027-01-31
- Completion
- 2027-01-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Venous Thrombo-Embolism Imaging Database (VTE-ID)
NCT06258694 ·Status: COMPLETED
-
The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study
NCT03835780 ·Status: COMPLETED
-
A New Clinic-Genetic Risk Score for Predicting Venous Thromboembolic Events in Cancer Patient
NCT03114618 ·Status: COMPLETED
-
Angioplasty-stenting vs Optimal Medical Treatment on Post-thrombotic Syndrome Reduction
NCT04250025 ·Status: RECRUITING ·Phase: NA
-
Immunogenetics of Heparin-Induced Thrombocytopenia: Aim 2
NCT02526485 ·Status: COMPLETED
-
Clarification of Optimal Anticoagulation Through Genetics
NCT00839657 ·Status: COMPLETED ·Phase: PHASE3
-
Validation of International Warfarin Pharmacogenetics Consortium (IWPC) Algorithm in Elderly Patients With Comorbidity
NCT02069132 ·Status: UNKNOWN
-
Predictors of Anticoagulation Control on Warfarin Therapy
NCT00905177 ·Status: COMPLETED
-
Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in Obesity
NCT00608465 ·Status: TERMINATED ·Phase: PHASE4
-
Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)
NCT00634907 ·Status: COMPLETED ·Phase: NA
-
Effect of Aging on Haemostasis Parameters
NCT00299624 ·Status: COMPLETED
-
Detection of Factor V Leiden G1691A and Factor II (Prothrombin) G20210A Point Mutations in DNA
NCT00959504 ·Status: COMPLETED
-
Risk Factors and Prediction Model of Cancer-associated Venous Thromboembolism
NCT05729464 ·Status: UNKNOWN
-
Assessment of Thrombotic Status in Patients With Acute Coronary Syndrome
NCT02562690 ·Status: UNKNOWN
-
The Protrieve PROTECTOR Study
NCT06495996 ·Status: COMPLETED ·Phase: NA
-
Efficacy of the Use of Risk Scores in Reducing Important Clinical Outcomes in Hospitalized Medical Ill Patients
NCT04267718 ·Status: COMPLETED ·Phase: NA
-
Understanding Risk Factors Involved in Developing a Second Blood Clot.
NCT00261014 ·Status: UNKNOWN
-
Prognostic Value of NETosis Markers for Thrombosis During Myeloproliferative Neoplasms (AVATARE)
NCT07119970 ·Status: RECRUITING ·Phase: NA
-
Patient Convenience Study
NCT02597920 ·Status: COMPLETED
-
In Vivo Detection of Circulating Clots in Patients With Thromboembolism
NCT05301348 ·Status: RECRUITING ·Phase: NA
-
Study of the Prognostic Value of the Coagulolytic Balance Dependent on Circulating Microvesicles in the Occurrence of Thrombotic Events After Total Knee Replacement in Orthopedic Surgery.
NCT05387694 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Clinical and Economic Burden of Bleeding Events in Patients in the UK With Non-valvular Atrial Fibrillation Treated With Vitamin k Antagonists
NCT02661516 ·Status: COMPLETED
-
Description of Patients With Acute Venous Thromboembolism in the UK's Clinical Practice Research Datalink Linked With Hospital Episode Statistics Dataset (CPRD-HES)
NCT02661568 ·Status: COMPLETED
-
Genetic Drivers,Risk Factors and Management Strategies on Survival and Clinical Outcomes in Visceral Venous "Thrombosis"
NCT07329725 ·Status: ACTIVE_NOT_RECRUITING
-
Genetic Epidemiology of Venous Thromboembolism
NCT00005543 ·Status: COMPLETED