MedTrace Logo

Impact of Iridotomy/Iridectomy Size on Postoperative Pupillary Block and Dysphotopsia Following DMEK

NCT07577635 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-05-11

No results posted yet for this study

Summary

Descemet membrane endothelial keratoplasty (DMEK) is the standard surgical treatment for corneal endothelial disorders. A postoperative pupillary block may occur despite routine preoperative laser iridotomy or intraoperative surgical iridectomy. Insufficient size or incomplete patency of the iridotomy/iridectomy (IT) may contribute to this complication, while excessively large openings may be associated with postoperative dysphotopsia. This prospective observational study investigates the association between IT size measured by anterior segment optical coherence tomography (AS-OCT) and the occurrence of postoperative pupillary block and dysphotopsia after DMEK.

Conditions

  • Pupillary Block After DMEK
  • Laser Iridotomy / Surgical Iridectomy
  • Dysphotopsia
  • Descemet Membrane Endothelial Keratoplasty (DMEK)

Interventions

DIAGNOSTIC_TEST

Anterior Segment Optical Coherence Tomography (AS-OCT)

Additional anterior segment OCT imaging of the iris to quantify the size and patency of the iridotomy or iridectomy in DMEK patients, performed as a non-invasive, contact-free study-related diagnostic procedure alongside routine clinical examinations.

OTHER

Dysphotopsia Questionnaire

Structured patient questionnaire to assess occurrence and severity of new postoperative dysphotopsia after DMEK.

Sponsors & Collaborators

  • University of Leipzig

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-01
Primary Completion
2027-01-01
Completion
2027-07-01

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07577635 on ClinicalTrials.gov