A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
NCT07571746 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 43
Last updated 2026-05-06
Summary
The purpose of this study is to assess the safety, tolerability, pharmacokinetic, and efficacy of surovatamig administered by subcutaneous injection in adult participants with primary membranous nephropathy.
Conditions
Interventions
- DRUG
-
Surovatamig
Participants will receive Surovatamig subcutaneously
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-28
- Primary Completion
- 2028-04-24
- Completion
- 2029-10-15
- FDA Drug
- Yes
Countries
- United States
- Belgium
- France
- Germany
- Italy
- Poland
- Spain
- United Kingdom
Study Locations
More Related Trials
-
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
NCT05624723 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of LY3473329 in Participants With Impaired and Normal Renal Function
NCT05778864 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Effects of AZD6140 in Patients With Renal Impairment and in Healthy Volunteers
NCT00733265 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
NCT05624710 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234
NCT06845813 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis
NCT00750295 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004
NCT06742762 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Pharmacokinetics, Safety and Tolerability of MEDI0382 in Renal Impairment Subjects
NCT03235375 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study of AZD5672 in Renally Impaired Subjects
NCT00715702 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Severe Renal Impairment or End Stage Renal Disease
NCT07559396 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Study of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment or Stage 5 Renal Impairment Requiring Hemodialysis
NCT01833754 ·Status: COMPLETED ·Phase: PHASE1
-
Study of GBT021601 in Participants With Renal Impairment
NCT05878704 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of S-892216-PO in Participants With Renal Impairment and Matched Controls
NCT07217886 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Assess S-217622 in Participants With Renal Impairment and Healthy Participants
NCT05363215 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Randomized, Open-label, Multicenter Clinical Study Evaluating the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of SHR-2173 Injection in Patients With Primary Membranous Nephropathy
NCT07289763 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease
NCT04492722 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of LY3502970 in Participants With Normal and Impaired Renal Function
NCT05936138 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study of AB023 (Xisomab 3G3) in End Stage Renal Disease Patients on Chronic Hemodialysis
NCT03612856 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY3819469 in Participants With Impaired and Normal Renal Function
NCT05841277 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function
NCT01367509 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
NCT05797610 ·Status: RECRUITING ·Phase: PHASE3
-
Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition in Japan.
NCT04626505 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Inclisiran in Participants With Renal Impairment Compared to Participants With Normal Renal Function (ORION-7)
NCT03159416 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy
NCT05834738 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN9035 in Healthy Adult Volunteers and Mildly Hypertensive Participants
NCT05291546 ·Status: COMPLETED ·Phase: PHASE1