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Comparison Between Pregabalin and Acetaminophen for the Treatment of Post-Mastectomy Pain Syndrome

NCT07567924 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 158

Last updated 2026-05-11

No results posted yet for this study

Summary

The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing mastectomy or breast-conservation (BCS). It could be burning, stabbing, shooting pain or pins-and-needle sensation.

Participants will:

* Take their prescribed allotted medicine for 14 days.
* Will visit the clinic at 2 and 6 week interval for assessment.

Conditions

  • Post Mastectomy Pain Syndrome

Interventions

DRUG

Pregabalin

1 tablet of 75 mg taken orally, once daily at night for 14 days, without interruption.

DRUG

Acetaminophen

2 tablets of 500mg, taken orally, three times a day, 8 hours apart, for 14 days, without interruption.

Sponsors & Collaborators

  • Sindh Institute of Urology and Transplantation

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-06
Primary Completion
2026-05-15
Completion
2026-05-15

Countries

  • Pakistan

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07567924 on ClinicalTrials.gov