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Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease

NCT07563491 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 824

Last updated 2026-05-04

No results posted yet for this study

Summary

Local literature is deprived of data comparing the effectiveness of esomeprazole and vonoprazan in patients with gastroesophageal reflux disease (GERD). This study was planned with the objective of comparing the effectiveness of esomeprazole versus vonoprazan in patients diagnosed with GERD.

Conditions

  • Gastro Esophageal Reflux

Interventions

DRUG

Esomeprazole

Patients received a once-daily dose of 20 mg of esomeprazole after the evening meal for 4 weeks.

DRUG

Vonoprazan

Patients received a once-daily dose of 20 mg of vonoprazan after the evening meal for 4 weeks.

Sponsors & Collaborators

  • Muhammad Aamir Latif

    lead OTHER

Principal Investigators

  • Faraz Ahmad · Allama Iqbal teaching hospital Dera Ghazi Khan

  • Mujahid Iqbal, FCPS · Allama Iqbal teaching hospital Dera Ghazi Khan

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2025-09-30
Completion
2025-09-30

Countries

  • Pakistan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07563491 on ClinicalTrials.gov