Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer

Summary

The goal of this clinical trial is to develop and evaluate an Artificial Intelligence Assisted Prehabilitation Program (AI APP) for returning to work and cost-effectiveness analysis in patients with oral cancer (OC). The main questions it aims to answer are:

* What kinds of needs are related to returning to work (RTW) in patients with OC from diagnosis to survival that we can incorporate into the development of AI APP to assist this population ?
* How is the effect of the AI APP that based on findings from the first question for patients with OC on physical and psychological distress, fear of recurrence, self-efficacy in coping with cancer, communication, motor function, quality of life, and RTW?
* How is the effect of the RTW AI prediction model to identify high-risk groups ? And how is the comprehensive cost effectiveness of benefits and quality of life of the AI APP for OC population?

Researchers will compare patients without using AI APP to see if the AI APP works to assist with coping physical and psychological distress, communication, motor function, quality of life, and RTW issues for individuals with OC?

Participants will:

* Be asked to fulfill a structural questionnaire, or engage in a semi-structured one-by-one interview or a focus group to assess their physical, psychological, and social support needs in the first stage.
* Be invited to participant the pilot testing of AI APP in the second stage.
* Be provided and trained by 3-month AI APP for 3 months or cared as usual in the third stage.
* Complete a structural questionnaire and follow up one year, including the baseline (before using the AI app) and at 1-2 weeks, 3 months, 6 months, 9 months, and 12 months after the baseline.
* Engage in one-by-one interview or a focus group to assess user experiences of the AI APP.

Conditions

• Oral Cancer
• Psychological Distress
• Communication Aids for Disabled
• Physiotherapy
• Return to Work
• Prehabilitation
• Physical Symptom Distress
• Motor Function
• Rehabilitation
• Quality of Life
• Cost Effectiveness
• Artifical Intelligence
• Prediction Model
• Case Management, APP(Application)

Interventions

DEVICE

Prehabilitation application

Participants will use an Artificial Intelligence Assisted Prehabilitation Program Application (AI Assisted Prehabilitation APP, AI APP), including Generative AI Assisted Psychosocial Support chat, AI-Based Postural Correction Programs Physiotherapy Prehabilitation, and Intelligent Learning-Based Communication Navigation Assistance System to assist individuals with OC dealing with their physical and psychological distress, motor function and communication issues, and social support throughout prehabilitaion and rehabilitation to help them better returning to work.

BEHAVIORAL

Conventional physiotherapy

jaw, neck, shoulder ROM exercises, and scapular-focused exercises, 30 minutes of intervention, once a week, and a total of 12 weeks

BEHAVIORAL

Scar management

scar massage and jaw-mobilizing exercises combined with devices or depressors

BEHAVIORAL

AI-based physiotherapy

jaw, neck, shoulder ROM exercises, and scapular-focused exercises guided by AI technology, 30 minutes of intervention, once a week, and a total of 12 weeks

Sponsors & Collaborators

• National Taiwan University Hospital

  collaborator OTHER

• National Yang Ming Chiao Tung University Hospital

  collaborator OTHER

• Taipei Veterans General Hospital, Taiwan

  lead OTHER_GOV

Study Design

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

20 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-09-27

Primary Completion

2028-07-31

Completion

2029-12-01

Countries

• Taiwan

Study Locations