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PRP vs PRF in Management of Striae Distensae

NCT07561671 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-05-07

No results posted yet for this study

Summary

A split-side comparative clinical study evaluating the efficacy and safety of injectable platelet-rich fibrin (PRF) versus platelet-rich plasma (PRP), alone or combined with microneedling, in the treatment of striae distensae. Thirty patients received PRF or PRP on one side and combination therapy with microneedling on the contralateral side over five sessions. Outcomes included striae width, length, severity score, and patient satisfaction

Conditions

  • Striae Distensae

Interventions

BIOLOGICAL

PRF group

Autologous platelet-rich fibrin prepared via single-spin centrifugation without anticoagulant and injected intradermally

BIOLOGICAL

PRP injection

Intradermal injection of platelet-rich plasma

DEVICE

PRF and microneedling

Performed using a dermapen device with 1 mm needle depth, followed by topical application of PRF.

DEVICE

PRP and microneedling

Performed using a dermapen device with 1 mm needle depth, followed by topical application of PRP.

Sponsors & Collaborators

  • Zagazig University

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-02
Primary Completion
2025-09-25
Completion
2026-02-17

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07561671 on ClinicalTrials.gov