MedTrace Logo

Study to Evaluate the Effect of Food and a Proton Pump Inhibitor on the Pharmacokinetics of VRN101099 in Healthy Adult Participants

NCT07550946 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-04-24

No results posted yet for this study

Summary

This Clinical trial is being done to understand how food and a common stomach-acid reducing medicine (called a proton pump inhibitor-PPI) affect how the body absorbs a new drug, VRN101099, in healthy adults.

Researchers will measure how much of the drug gets into the bloodstream and how fast it gets there in each situation.

This will help identify the most effective way for future patients to use VRN101099 in the treatment of solid tumors and cancers.

The main questions it aims to answer is:

1. Does food or a PPI change how the body absorbs a single dose of VRN101099?
2. Is a single dose of VRN101099 safe and well tolerated when taken with or without food or a PPI?
3. How is VRN101099 removed through urine when taken with or without food or a PPI?

Conditions

  • Healthy Adult

Interventions

DRUG

VRN101099

Type: Capsule form Route of administration: Oral

Sponsors & Collaborators

  • Voronoi, Inc

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-12
Primary Completion
2026-09-01
Completion
2026-09-30

Countries

  • Australia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07550946 on ClinicalTrials.gov