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Epidemiology And Risk Factors Of Intradialytic Hypotension In Maintenance Hemodialysis Patients

NCT07545629 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 395

Last updated 2026-04-22

No results posted yet for this study

Summary

This prospective, multicenter observational study aims to describe how often intradialytic hypotension (IDH) occurs and to identify its risk factors in adult patients receiving maintenance hemodialysis. Intradialytic hypotension is a common complication during dialysis that can lead to symptoms, organ hypoperfusion, and interruption of treatment.

Participants will be adults on regular maintenance hemodialysis who meet predefined inclusion and exclusion criteria. Routine clinical information will be collected, including demographics, primary kidney disease, comorbidities, medications, dialysis vintage, dialysis prescription (ultrafiltration volume and rate, dialysate composition, treatment time), and standard laboratory tests. During a defined observation period, blood pressure and related symptoms will be recorded across dialysis sessions to document the frequency, severity, and patterns of IDH.

The main goals are to estimate the incidence and prevalence of intradialytic hypotension in maintenance hemodialysis patients and to explore potential risk factors, such as patient characteristics, cardiovascular status, volume status, and dialysis-related parameters. The findings may help clinicians better recognize patients at high risk of IDH and optimize dialysis prescriptions and monitoring strategies to reduce the occurrence of IDH and its adverse consequences.

Conditions

  • Intradialytic Hypotension
  • End-stage Renal Disease (ESRD)
  • Chronic Kidney Failure
  • Chronic Kidney Disease, Stage IV (Severe)
  • Hemodialysis

Sponsors & Collaborators

  • Wuhu City Second People's Hospital

    collaborator OTHER

  • Wuhu County Traditional Chinese Medicine Hospital

    collaborator OTHER

  • First Affiliated Hospital of Wannan Medical College

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-15
Primary Completion
2025-02-28
Completion
2025-12-29

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07545629 on ClinicalTrials.gov