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Pancreatic Resection in Fit Octogenarians With Nonmetastatic Pancreatic Cancer

NCT07542782 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2048

Last updated 2026-04-21

No results posted yet for this study

Summary

This study looks at how different treatment approaches affect survival in older people with pancreatic cancer that has not spread to other parts of the body. In particular, it focuses on patients aged 80 years and older who are still in relatively good general health and able to carry out normal daily activities.

Pancreatic cancer is a serious disease, and surgery to remove the tumor is often the only treatment that offers a chance of longer survival. However, older patients are less likely to receive surgery, even if they are otherwise fit. Doctors may hesitate to recommend surgery mainly because of the patient's age, rather than their overall health condition. This study aims to better understand whether surgery can still be beneficial for these older patients.

The study also examines the role of additional treatment after surgery, such as chemotherapy. In real-world medical practice, not all patients receive this follow-up treatment, especially older individuals who may have a slower recovery after surgery. This can make it difficult to understand whether such treatments truly improve survival.

To answer these questions, the study uses data from a large cancer registry in Germany. It compares patients who had surgery with those who did not, and it also looks at patients who received additional treatment after surgery versus those who did not. Special methods are used to take into account that some patients may not have been able to receive further treatment because they did not recover well enough after surgery.

The results of this study are intended to help doctors make better treatment decisions for older patients with pancreatic cancer, focusing more on their overall health and less on age alone.

Conditions

Interventions

PROCEDURE

All types of surgical tumor resection procedures with curative intent

PROCEDURE

No surgical resection

Sponsors & Collaborators

  • Clinical-Epidemiological Cancer Registry Brandenburg Berlin, Cottbus, Germany

    collaborator UNKNOWN

  • Medizinische Hochschule Brandenburg Theodor Fontane

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2023-12-31
Completion
2024-10-12

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07542782 on ClinicalTrials.gov