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Hepatoprotective Effects of Reishi Mushroom- (Ganoderma Lucidum) Among Metabolic Dysfunction-associated Fatty Liver Disease Patients

NCT07534241 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2026-04-16

No results posted yet for this study

Summary

This 12-week RCT investigates the hepatoprotective and immunomodulatory effects of Ganoderma lucidum combined with a probiotic-rich diet in adults with MAFLD, assessing liver enzymes, lipid profile, inflammation, gut microbiota, and oxidative stress.

Findings are expected to show dose-dependent improvements in hepatic fat, insulin resistance, and inflammatory markers, potentially reducing reliance on pharmacotherapy in

Conditions

  • Lipid Profile
  • Liver Biomarkers

Interventions

DIETARY_SUPPLEMENT

reishi mushroom- (Ganoderma lucidum)

Each capsule contains 250 mg of Reishi mushroom dried powder, to be taken alongside a probiotic-rich diet.

DIETARY_SUPPLEMENT

Placebo

STARCH CAPCULE

DIETARY_SUPPLEMENT

Reishi mushroom dried powder

Reishi mushroom dried powder ONCE A DAY

DIETARY_SUPPLEMENT

Reishi mushroom dried powder

Reishi mushroom dried powder TWICE A DAY

Sponsors & Collaborators

  • University of Lahore

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-02
Primary Completion
2026-02-01
Completion
2026-04-15

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07534241 on ClinicalTrials.gov