A Prospective Observational Study of Changes in Cortisol Levels After Neoadjuvant Immunotherapy and Their Prognostic Value in Patients With NSCLC
NCT07530276 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 330
Last updated 2026-04-15
Summary
This study is an open, prospective and observational clinical trial. Adopting a prospective cohort study design, it selects patients with non-small cell lung cancer who receive neoadjuvant immunotherapy as the research subjects. Through systematic follow-up, it monitors the dynamic changes of cortisol levels of patients at different treatment stages and after surgery, and analyzes the associations between these changes and disease progression, treatment effect and adverse reactions.
Conditions
Sponsors & Collaborators
-
Guangdong Provincial People's Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-08-30
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- China
Study Locations
More Related Trials
-
Efficacy of Neoadjuvant Immunotherapy in Patients With Lung Cancer
NCT07166003 ·Status: RECRUITING
-
Perioperative Treatment Outcomes of Early NSCLC
NCT06610240 ·Status: ENROLLING_BY_INVITATION
-
The Associations of Psychological Stress With Therapy Efficacy and Prognosis of Lung Cancer (STRESS-LUNG)
NCT05477979 ·Status: RECRUITING
-
A Study to Explore the Role and Impact of Wearable Smart Devices in Perioperative NSCLC Patients
NCT06118229 ·Status: RECRUITING
-
ctDNA Dynamic Monitoring and Its Role of Prognosis in Stage I NSCLS by NGS
NCT03172156 ·Status: COMPLETED
-
A Study of Participants in China With Non-Small-Cell Lung Cancer That is Unable to be Treated With Surgery
NCT05872763 ·Status: ACTIVE_NOT_RECRUITING
-
Circulating Immune Markers for Prognostic Evaluation in Postoperative Lung Cancer Patients
NCT07242482 ·Status: NOT_YET_RECRUITING
-
Comparison of Inflammatory Cytokine Levels Between Single-port and Three-port Thoracoscopic Lobectomy in the Treatment of Non-small Cell Lung Cancersurgery on Perioperative Clinical Indexes、Inflammatory Reaction and Quality of Life Scores of Patients With Non-small Cell Lung Cancer
NCT05070026 ·Status: COMPLETED ·Phase: NA
-
Prognostic Correlation Between the Ratio of the Neutrophil Ratio to the Ratio of CD4+/CD8+ T Cells in Patients With Advanced Non-small Cell Lung Cancer NSCLC) Undergoing Immunotherapy Combined With Chemotherapy
NCT06954259 ·Status: ACTIVE_NOT_RECRUITING
-
Exploration of Predictive Markers of Neoadjuvant Immunotherapy in Non-Small Cell Lung Cancer
NCT05965557 ·Status: RECRUITING
-
Prospective Observation of Failure Patterns in NSCLC Treated With ICIs
NCT04492969 ·Status: UNKNOWN
-
Prognostic Significance of the Uncertain Resection in NSCLC
NCT06511661 ·Status: ACTIVE_NOT_RECRUITING
-
Factors Determining the Prognosis in NSCLC Stage IV
NCT04306094 ·Status: UNKNOWN
-
A Prospective, Observational Trial on the Diagnostic and Prognostic of LM
NCT02607605 ·Status: UNKNOWN
-
Effect of Exercise Therapy on Psychological State and Clinical Prognosis of Advanced Non-small Cell Lung Cancer
NCT05959265 ·Status: UNKNOWN ·Phase: NA
-
Prognostic and Dynamic Change of CTC Enumeration in Advanced NSCLC With Chemotherapy and Targeted Therapy
NCT02155426 ·Status: UNKNOWN
-
Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer
NCT07035860 ·Status: NOT_YET_RECRUITING
-
Adjuvant Chemotherapy for High-Risk Pathologic Stage I Non-Squamous NSCLC
NCT07250360 ·Status: COMPLETED
-
Integrative Multi-Omics Testing for Immunotherapy Response in Non-Small Cell Lung Cancer
NCT05928299 ·Status: COMPLETED
-
Clinicopathological Characteristics and Prognosis Analysis of Stage IB Non-small Cell Lung Cancer
NCT05979623 ·Status: COMPLETED
-
A Study to Evaluate Effectiveness and Safety of Surgeries in Elderly NSCLC Patients
NCT03429673 ·Status: COMPLETED
-
Study on Systemic and Airway Cytokines and Oxidative Stress in Lung Cancer Patients Undergoing Surgery
NCT00956852 ·Status: TERMINATED
-
Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion
NCT04263688 ·Status: UNKNOWN
-
Impact of Psychological Stress on Treatment Response and Prognosis in Lung Cancer Patients
NCT06964503 ·Status: NOT_YET_RECRUITING
-
Diagnostic Significance of Single Center, Open and Prospective Evaluation of <Sup>18<Sup>F-FDG PET/CT Dynamic Imaging and Genomic Sequencing in Detecting Metastatic Lesions and Differentiating Multiple Primary Lung Cancer From Intrapulmonary Metastases of Non-small Cell Lung Cancer
NCT03679936 ·Status: UNKNOWN