Evaluate the Efficacy and Safety of GZR33 Injection in Patients With Type 2 Diabetes
NCT07527078 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 350
Last updated 2026-07-01
Summary
Evaluate the efficacy of GZR33 Injection and Insulin Degludec Injection (Tresiba®) in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Oral Antidiabetic Drugs.
Conditions
- Type 2 Diabetes (T2DM)
Interventions
- DRUG
-
GZR33 Injection
GZR33 Injection Administered SC, once-daily
- DRUG
-
Insulin Degludec Injection (Tresiba®)
Administered SC, once-daily
Sponsors & Collaborators
-
Gan & Lee Pharmaceuticals.
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-07
- Primary Completion
- 2026-04-07
- Completion
- 2027-04-17
Countries
- China
Study Locations
More Related Trials
-
A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics
NCT04663282 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of THDB0206 Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes
NCT07282054 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes
NCT03882970 ·Status: COMPLETED ·Phase: PHASE3
-
Investigating the Safety and Effectiveness of Insulin Degludec in a Real World Population With Type 1 and 2 Diabetes Mellitus
NCT02392117 ·Status: COMPLETED
-
In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus
NCT00354536 ·Status: COMPLETED ·Phase: PHASE2
-
A Research Study, Looking at How Tresiba® Works in People With Type 2 Diabetes in Local Clinical Practice in Saudi Arabia
NCT03785522 ·Status: COMPLETED
-
A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM)
NCT02759107 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study to Compare the Bioavailability of HR17031 in Healthy Subjects at Different Sites
NCT06086912 ·Status: COMPLETED ·Phase: PHASE1
-
A Non-interventional, Post Marketing Surveillance (PMS) Study of Tresiba® (Insulin Degludec) to Evaluate Long Term Safety and Efficacy in Patients With Diabetes Mellitus in Routine Clinical Practice in India
NCT02117622 ·Status: COMPLETED
-
Injection Site Study In Patients With Type 2 Diabetes Mellitus (T2DM) And Healthy Volunteers
NCT00394030 ·Status: COMPLETED ·Phase: PHASE1
-
First Time in Human Study Using GSK2330672
NCT01416324 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes
NCT06326047 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
NCT06297603 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
The Efficacy and Safety of Insulin Degludec/Liraglutide Combination (IDegLira) in Patients With Type 2 Diabetes
NCT06408532 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
A Study to Evaluate Safety and Effectiveness in Patients of All Age Groups Excluding Less Than 12 Months Old Infants With Diabetes Mellitus in Routine Clinical Practice in Korea
NCT02779413 ·Status: COMPLETED
-
A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin
NCT07215312 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
NCT06260722 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)
NCT06280703 ·Status: RECRUITING ·Phase: PHASE1
-
Post-Marketing Surveillance Study: 12 To 24 Weeks Study On The Treatment Emergent Adverse Events In Patients With Type 2 Diabetes Taking Exenatide In Korea
NCT02090673 ·Status: COMPLETED
-
Study of the Efficacy and Safety of Inhaled Technosphere Insulin in Patients With Type 2 Diabetes
NCT00511602 ·Status: COMPLETED ·Phase: PHASE2
-
To Investigate the Blood Concentration of Liraglutide as Well as the Effects on Glucose and Insulin After 21 Days of Daily Subcutaneous Injections of Liraglutide or Placebo
NCT00761540 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study to See How Well Weekly Insulin Icodec Maintains Blood Sugar Levels Compared to Daily Basal Insulins in Adults With Type 2 Diabetes
NCT07112339 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Short-Term Intensive Insulin Sequential Exenatide Therapy in Newly Diagnosed Type 2 Diabetic Patients
NCT01776788 ·Status: COMPLETED ·Phase: PHASE4
-
A Pilot Study Investigating Bioequivalence Between a Single Dose of Formulation 2 and Formulation 3 of MEDI0382
NCT03341013 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy and Safety of Exenatide Once-Weekly Injection Compared to Once-Daily Insulin in Type 2 Diabetes Mellitus
NCT00935532 ·Status: COMPLETED ·Phase: PHASE3