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Comparison Between Different Concentrations of Ozone Gas as an Intra-articular Injection for Treatment of Internal Derangement of Tempromandibular Joint

NCT07523451 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-06-25

No results posted yet for this study

Summary

The intra-articular injection is considered the first line of minimally invasive treatment of joint disease as it has an analgesic, antimicrobial effect and an immune system stimulating action as it is one of the most powerful detoxication agents.

Conditions

  • TMJ Disc Disorder

Interventions

OTHER

Patients will be treated with 2ml ozone oxygen mixture with concentration 6 micron/ml

Patients will be treated with 2ml ozone oxygen mixture with concentration 6 micron/ml

OTHER

Patients will be treated with 2ml ozone oxygen mixture with concentration 12 micron/ml

Patients will be treated with 2ml ozone oxygen mixture with concentration 12 micron/ml

Sponsors & Collaborators

  • Alexandria University

    lead OTHER

Principal Investigators

  • yehia A El-Mahallawy, Phd · Faculty of Dentistry, Alexandria University, Alexandria, Alexandria

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-01
Primary Completion
2025-10-30
Completion
2026-04-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07523451 on ClinicalTrials.gov