Comparison Between Efficacy of Topical Tranexamic Acid Vs Topical Ethyl Ascorbic Acid In Treatment Of Melasma
NCT07522788 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 128
Last updated 2026-04-13
Summary
This study is to compare the efficacy of topical tranexamic acid vs topical ethyl ascorbic acid in the treatment of melasma
Conditions
- Melasma
Interventions
- DRUG
-
Ethyl ascorbic acid topical application
The participants in this arm of study will only receive topical ethyl ascorbic acid once daily at night for 12 weeks
- DRUG
-
Tranxemic acid topical application
The participants in this arm will receive only topical tranexamic acid once daily for 12 weeks
Sponsors & Collaborators
-
Hayatabad Medical Complex
lead OTHER_GOV
Principal Investigators
-
aneeqa khan · Hayatabad Medical Complex
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-06-01
- Primary Completion
- 2026-11-30
- Completion
- 2026-11-30
More Related Trials
-
Tranexamic Acid vs. Combination With Fractional Carbon Dioxide Laser in Melasma
NCT03899233 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparison of Azelaic Acid 20 % Cream Versus Hydroquinone 4% Cream as an Adjuvant to Oral Tranexamic Acid in Melasma
NCT05887219 ·Status: COMPLETED ·Phase: PHASE1
-
The Effectiveness of 3% Topical Tranexamic Acid Compared to 4% Topical Hydroquinone as Therapy of Melasma
NCT06010810 ·Status: UNKNOWN ·Phase: PHASE3
-
Ultrasound-Enhanced Delivery of Compound TXA Solution in Melasma
NCT07202156 ·Status: RECRUITING ·Phase: NA
-
Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma
NCT07448415 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma
NCT03751163 ·Status: COMPLETED ·Phase: PHASE3
-
Oral Tranexamic Acid and Laser for Treatment of Melasma
NCT03686787 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma
NCT07495748 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study
NCT07060157 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study
NCT04697992 ·Status: COMPLETED ·Phase: NA
-
Comparison of Intralesional Tranexamic Acid and Platelets Rich Plasma in the Treatment of Melasma
NCT05884151 ·Status: COMPLETED ·Phase: PHASE1
-
Oral and Topical Tranexamic Acid for the Treatment of Melasma
NCT03585179 ·Status: UNKNOWN ·Phase: PHASE3
-
Fractional co2 Laser Followed by Either Vitamin c or Tranexamic Acid in Treatment of Melasma.
NCT05911698 ·Status: UNKNOWN ·Phase: NA
-
Tranexamic Acid With Microneedling in Melasma
NCT05909072 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparison of Effectiveness of Tranexamic Acid Mesotherapy Versus Glutathione Mesotherapy in Post Burn Facial Hyperpigmentation
NCT07263841 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Evaluation of Laser and Tranexamic Acid in Treatment of Melasma
NCT04599205 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Tranexamic Acid vs Fractional CO2 Laser in Post-acne Hyperpigmentation
NCT03765021 ·Status: UNKNOWN ·Phase: NA
-
Treatment of Melasma With Yellow Light Compared to Tranexamic Acid
NCT05326997 ·Status: TERMINATED ·Phase: NA
-
Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid
NCT03153852 ·Status: UNKNOWN ·Phase: PHASE4
-
Azelaic Acid 20% vs Hydroquinone 4% in Epidermal Melasma
NCT07327983 ·Status: COMPLETED ·Phase: NA
-
Tranexamic Acid in Treatment of Facial Erythema
NCT05897918 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety Trial of Using Ultra-Pulsed Shockwaves to Deliver Tranexamic Acid for the Treatment of Melasma
NCT06418568 ·Status: RECRUITING ·Phase: NA
-
A Clinical Observation of 1064-nm Q-Switched Fractional Laser Combined With Oral Tranexamic Acid on Treating of Melasma.
NCT03963466 ·Status: COMPLETED ·Phase: NA
-
Treatment of Freckles by Intradermal Tranexamic Acid Versus Q Switched KTP Laser.
NCT03885895 ·Status: UNKNOWN ·Phase: PHASE1
-
Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid
NCT06522984 ·Status: RECRUITING ·Phase: NA