Tolerability of Ropeginterferon Alfa-2b Add-on to Ongoing Ruxolitinib Therapy in Myelofibrosis (RopeRux in Myelofibrosis)
NCT07521046 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2026-04-17
Summary
The purpose of this clinical trial is to learn if the study drug ropeginterferon alfa- 2b added to, standard of care, ruxolitinib is safe and effective in treating patients with Myelofibrosis.
Conditions
Interventions
- DRUG
-
ropeginterferon alfa- 2b
Ropeginterferon alfa- 2b will be administered as a subcutaneous injection every two weeks.
- DRUG
-
Ruxolitinib will be administered per standard of care.
Sponsors & Collaborators
-
PharmaEssentia
collaborator INDUSTRY - lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-31
- Primary Completion
- 2029-05-31
- Completion
- 2030-05-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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