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Pupillary Dilator Muscle Thickness as a Potential Predictor of Intraoperative Floppy Iris Syndrome

NCT07517094 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-04-08

No results posted yet for this study

Summary

Intraoperative Floppy Iris Syndrome (IFIS) is a potencial complication encountered during cataract surgery in patients treated with α1-adrenergic receptor antagonists (α1-ARAs) for lower urinary tract symptoms. Therefore, careful assessment of pharmacological history is essential during the preoperative biometric evaluation of patients indicated for cataract surgery. In this study, the investigators expand the standart preoperative assessment by incorporating measurements of iris thickness at the level of the dilator and sphincter pupillae muscles, as well as pupil diameter, using anterior segment optical coherence tomography in patients receiving α1-ARAs. The aim of the study was to determine whether these parameters are associated with the intraoperative risk of IFIS development.

Conditions

  • Intraoperative Floppy Iris Syndrome
  • Cataract
  • Age-related Cataract
  • Adrenergic Receptor Antagonist Adverse Reaction

Sponsors & Collaborators

  • Palacky University

    collaborator OTHER

  • University Hospital Olomouc

    lead OTHER

Principal Investigators

  • Miroslava Maluskova, MD, FEBO · University Hospital Olomouc and Palacky University Olomouc

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-03
Primary Completion
2024-05-31
Completion
2024-05-31

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07517094 on ClinicalTrials.gov