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The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic.

NCT07515612 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2026-04-07

No results posted yet for this study

Summary

This randomized controlled clinical trial aims to evaluate and compare the effectiveness of chamomile extract and valerian extract in reducing dental anxiety in healthy pediatric patients aged 6 to 10 years undergoing tooth extraction. Participants will be randomly assigned to receive one of the herbal interventions or a placebo prior to extraction. Dental anxiety will be assessed using validated anxiety rating scales and physiological parameters. This study seeks to explore a safe, easy to apply, and effective approach to manage child behavior and reduce dental anxiety.

Conditions

  • Anxiety, Dental

Interventions

DIETARY_SUPPLEMENT

Valerian extract

Participants will receive 1 mL of valerian root liquid extract (Valeriana officinalis L., 1000 mg/mL), diluted in a small amount of apple juice, 30 minutes prior to local anesthesia and tooth extraction.

DIETARY_SUPPLEMENT

Chamomile extract

Participants will receive 2 ml of German chamomile flower liquid extract (Matricaria recutita, 2400 mg/2 mL), diluted in a small amount of water, 30 minutes prior to local anesthesia and tooth extraction.

OTHER

Water (Placebo)

Participants will receive a small amount of water 30 minutes prior to local anesthesia and tooth extraction.

Sponsors & Collaborators

  • Damascus University

    lead OTHER

Principal Investigators

  • Juman Hayo, DDS · Faculty of Dentistry, University of Damascus

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
6 Years
Max Age
10 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2026-04-15
Completion
2026-04-30

Countries

  • Syria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07515612 on ClinicalTrials.gov