MedTrace Logo

Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.

NCT07513012 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 82

Last updated 2026-04-06

No results posted yet for this study

Summary

In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients will be administered the same block on both sides (bilateral) and the effects in terms of post surgery pain during the 1st 24 hours, nausea vomiting, and the need and dosage of intravenous analgesic and antiemetic will be studied to see whether one technique is superior to the other or not.

Conditions

  • Post Operative Pain Control
  • PONV

Interventions

PROCEDURE

Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine

TAP block is a regional anesthesia technique used for post-operative analgesia in abdominal surgeries. TAP block was first described by Rafi et al in 2001, as a regional block, in which local anesthesia is injected through triangle of petit to achieve analgesia of the T6 to L1 thoracolumbar nerves as they pass through the plane between internal oblique and transversus abdominis muscles. This blocks the sensory nerves in the anterolateral abdominal wall. Right Unilateral TAP block has been used as a part of multimodal analgesia in Lap chole (LC), with favorable results.

PROCEDURE

Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine

TAP block is a regional anesthesia technique used for post-operative analgesia in abdominal surgeries. TAP block was first described by Rafi et al in 2001, as a regional block, in which local anesthesia is injected through triangle of petit to achieve analgesia of the T6 to L1 thoracolumbar nerves as they pass through the plane between internal oblique and transversus abdominis muscles. This blocks the sensory nerves in the anterolateral abdominal wall. Bilateral TAP block can be used as a part of multimodal analgesia in Lap chole (LC), because two of the ports (epigastric and umbilical) in Lap chole are in the midline and hence receive sensory supply from both right and left side.

Sponsors & Collaborators

  • King Edward Medical University

    lead OTHER

Principal Investigators

  • Aneeqah Din Muhammad, MBBS, MSurg · King Edward Medical University/ Mayo Hospital, Lahore

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-04
Primary Completion
2026-04-04
Completion
2026-04-04

Countries

  • Pakistan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07513012 on ClinicalTrials.gov