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Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM)

NCT07510984 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 721

Last updated 2026-04-14

No results posted yet for this study

Summary

The goal of this observational study is to learn whether heterotopic gastric mucosa (HGM) in the upper esophagus is associated with swallowing difficulties (dysphagia) in adults undergoing a medically indicated gastroscopy. The main questions it aims to answer are:

* Is the presence of HGM associated with dysphagia?
* Is the presence of HGM associated with dyspepsia and reduced health-related quality of life? Among participants reporting dysphagia, what is the distribution of oropharyngeal versus esophageal dysphagia, and is this related to the presence of HGM? If there is a comparison group: Researchers will compare participants with endoscopically confirmed HGM to participants without HGM to determine whether dysphagia, dyspepsia symptoms, and quality-of-life measures differ between groups.

Participants will:

Complete pseudonymised questionnaires about dysphagia, dyspepsia symptoms, and quality of life before the gastroscopy.

Undergo the medically indicated gastroscopy as planned; the endoscopist will assess whether HGM is present based on the endoscopic appearance, and routine endoscopy findings will be documented.

Conditions

  • Heterotopic Gastric Mucosa of the Proximal Esophagus
  • Gastric Inlet Patches
  • Dysphagia
  • Dyspepsia

Sponsors & Collaborators

  • Knappschaft Kliniken GmbH

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-24
Primary Completion
2027-03-24
Completion
2027-07-31

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07510984 on ClinicalTrials.gov