Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma
NCT07508098 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2026-04-02
Summary
study was conducted on middle aged male and female, including families and health care professional also.
Conditions
- Melasma (Facial Melasma)
Interventions
- DRUG
-
Triple combination cream
4.7% N-acetylcysteine, 2% Hydroquinone and 0.1 % triamcinolone acetate twice daily for 8 weeks
- DRUG
-
Hydroquinone 4% Cream
twice daily for 8 weeks
Sponsors & Collaborators
-
Pak Emirates Military Hospital
lead OTHER
Principal Investigators
-
QAMMAR khan DR, MBBS. FCPS(Dermatalogy) · Pak Emirates Military Hospital
-
Moizza tHAIR Dr, MBBS.FCPS(Dermatology) · Pak Emirates Military Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 15 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-18
- Primary Completion
- 2026-01-19
- Completion
- 2026-01-19
- FDA Drug
- Yes
Countries
- Pakistan
Study Locations
More Related Trials
-
Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma.
NCT06013540 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi
NCT07345507 ·Status: COMPLETED ·Phase: NA
-
A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma
NCT03049059 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Study to Evaluate the Effect of Facial Serum Q69 in Moderating the Appearance of Mild to Moderate Melasma
NCT05013801 ·Status: COMPLETED ·Phase: NA
-
Cysteamine Compared to Hydroquinone in Melasma
NCT05969587 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of a 4% Hydroquinone Cream for the Treatment of Melasma
NCT02095990 ·Status: COMPLETED ·Phase: PHASE3
-
EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMA
NCT06787846 ·Status: COMPLETED ·Phase: NA
-
Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma
NCT04170088 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma
NCT06278948 ·Status: RECRUITING ·Phase: NA
-
Ultraviolet and UV-Visible Light Photoprotection for the Treatment of Melasma
NCT01695356 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Intradermal Microinjections of Tanexamic Acid and Oral Tranexamic Acid in the Management of Melasma.
NCT07280234 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled Study
NCT06957834 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial of Hydroquinone Versus Miconazol in Melasma
NCT01661556 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES
NCT07121439 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Assessment of Atrophogenic Potential of Triple Combination Cream for Treatment of Melasma
NCT00469183 ·Status: COMPLETED ·Phase: PHASE4
-
Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid
NCT03153852 ·Status: UNKNOWN ·Phase: PHASE4
-
Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Participants With Moderate Facial Melasma
NCT02977507 ·Status: COMPLETED ·Phase: NA
-
Evaluation of an Herbal-Based De-Pigmenting System
NCT02138539 ·Status: COMPLETED ·Phase: PHASE4
-
Azelaic Acid Versus Hydroquinone in Melasma
NCT00927771 ·Status: UNKNOWN ·Phase: PHASE4
-
Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid
NCT00166192 ·Status: COMPLETED ·Phase: PHASE4
-
Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study
NCT07060157 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of Melasma
NCT03751163 ·Status: COMPLETED ·Phase: PHASE3
-
Combined Q-switched Nd:YAG Laser and Platelet Rich Plasma Versus Q- Switched Nd:YAG Laser Alone in Melasma
NCT04765930 ·Status: UNKNOWN ·Phase: NA
-
Azelaic Acid Iontophoresis Versus Topical Azelaic Acid Cream in the Treatment of Melasma
NCT00848458 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
NCT06253468 ·Status: RECRUITING ·Phase: NA