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Can Astaxanthin Help Manage Asthma in POlluted Areas?

NCT07507682 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2026-04-02

No results posted yet for this study

Summary

This study will test whether astaxanthin, a naturally occurring antioxidant supplement, can improve lung function, reduce airway inflammation, and improve asthma control in adults with mild-to-moderate asthma. Participants will receive astaxanthin and placebo in random order in a double-blind crossover design. Each treatment period lasts 4 weeks and is separated by a 3-week washout period. The study also measures indoor and personal air pollution exposure to examine whether pollution influences asthma symptoms, airway responsiveness, and response to treatment. Exploratory thoracic bioelectrical impedance spectroscopy will be assessed alongside standard respiratory tests.

Conditions

  • Asthma (Diagnosis)
  • Airway Inflammation
  • Airway Hyperresponsiveness

Interventions

DIETARY_SUPPLEMENT

Astaxanthin Oral Capsule

Natural astaxanthin derived primarily from Haematococcus pluvialis, administered orally as three 4 mg capsules daily (total 12 mg/day) with the participant's largest meal for 4

DIETARY_SUPPLEMENT

Matched Placebo (Capsules)

Matched placebo capsules administered orally once daily as three capsules with the participant's largest meal for 4 weeks.

Sponsors & Collaborators

  • AstaReal

    collaborator UNKNOWN

  • BodyStat Ltd.

    collaborator UNKNOWN

  • British Pest Control Association

    collaborator UNKNOWN

  • Middlesex University

    lead OTHER

Principal Investigators

  • Lygeri Dimitriou · Middlesex University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-05-15
Primary Completion
2026-07-20
Completion
2026-07-20

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07507682 on ClinicalTrials.gov