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Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

NCT07504172 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1700

Last updated 2026-03-31

No results posted yet for this study

Summary

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice.

In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are:

* How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching?
* How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

Conditions

  • Overweight , Obesity
  • Obesity (Disorder)

Interventions

DRUG

Tirzepatide

Initiating treatment with tirzepatide

Sponsors & Collaborators

  • Nederlandse Obesitas Kliniek

    collaborator OTHER

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Maria Hopman, MD, PhD · Radboud University Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-01
Primary Completion
2026-07-01
Completion
2026-08-01
FDA Drug
Yes

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07504172 on ClinicalTrials.gov