Exploratory Clinical Evaluation of Personalized Functional Profiling in GI Tumors: Predicting Drug Response in CRC and PDAC
NCT07500259 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 188
Last updated 2026-03-30
Summary
The ColoPan study evaluates the scientific validity, reproducibility, and predictive performance of the Personalised Functional Profiling (PFP) platform in colorectal cancer and pancreatic ductal adenocarcinoma patients. It combines genomic sequencing with in vitro functional drug testing using patient-derived spheroids/organoids.
Conditions
- Colorectal Cancer
- PDAC - Pancreatic Ductal Adenocarcinoma
Interventions
- OTHER
-
Personalized Functional Profiling
This is an observational study where biological samples are collected to provide Personalized Functional Profiling, an integrated strategy that combines genomic analysis with direct drug response assessments using patient-derived spheroids/organoids (PDSOs)
Sponsors & Collaborators
-
Hopitaux Robert Schuman
collaborator UNKNOWN -
Luxembourg Institute of Health
lead OTHER_GOV
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-01
- Primary Completion
- 2029-09-30
- Completion
- 2034-11-01
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