MedTrace Logo

Oropharyngeal Care With Colostrum, Chlorohexidine and Sodium Bicarbonate in Preventing Ventilator-associated Pneumonia in Preterm Neonates

NCT07482007 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-06-04

No results posted yet for this study

Summary

comparing the effect of oral care with colostrum, chlorohexidine and sodium bicarbonate in prevention of ventilator-associated pneumonia in preterm neonates.

Conditions

  • Ventilator-Associated Pneumonia

Interventions

OTHER

Oropharyngeal Care with Colostrum

Application of small amounts of expressed maternal colostrum to the oral mucosa of ventilated preterm neonates using sterile swabs every 3-4 hours according to NICU oral care protocol.

DRUG

Chlorhexidine Oral Care

Oropharyngeal care using diluted chlorhexidine solution applied to the oral cavity of ventilated preterm neonates at scheduled intervals according to NICU protocol.

OTHER

Sodium Bicarbonate oral care

Preterm neonates receiving oral care using sodium bicarbonate solution applied to the oral mucosa using sterile swabs.

OTHER

Normal Saline Oral Care

Routine oropharyngeal care using sterile normal saline applied with sterile swabs at regular intervals during mechanical ventilation.

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Dalia Ayoub · Tanta University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-04-01
Primary Completion
2026-01-01
Completion
2026-03-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07482007 on ClinicalTrials.gov