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Predictors and Long-term Incidence of In-stent Restenosis After Chronic Total Occlusion Percutaneous Coronary Intervention

NCT07473596 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 294

Last updated 2026-03-16

No results posted yet for this study

Summary

The goal of this clinical trial is to describe the long-term (≥ 3 years) patency of coronary artery stents following chronic total occlusion percutaneous coronary intervention (CTO PCI). The main questions it aims to answer are:

* What is the incidence of in-stent restenosis after CTO PCI?
* What are patient-, lesion-, and procedure-related factors associated with an increased risk of in-stent restenosis after CTO PCI?

Conditions

  • Coronary Artery Disease (CAD)
  • Chronic Total Occlusion of Coronary Artery
  • Chronic Total Occlusion (CTO)

Interventions

PROCEDURE

chronic total occlusion percutaneous coronary intervention (CTO PCI)

All patients in the study have received CTO PCI with a drug-eluting stent.

DIAGNOSTIC_TEST

coronary computed tomography angiography

Patients meeting the surveillance imaging criteria received computed tomography angiography.

DIAGNOSTIC_TEST

invasive coronary angiography

According to the study criteria, some of the patients received confirmation imaging with invasive coronary angiography after coronary computed tomography angiography.

Sponsors & Collaborators

  • Lauri Mansikkaniemi

    lead OTHER

Principal Investigators

  • Petri Laine, Ph.D. · Department of Cardiology, Heart and Lung Center, Helsinki University Central Hospital and University of Helsinki

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-16
Primary Completion
2025-02-06
Completion
2025-02-24

Countries

  • Finland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07473596 on ClinicalTrials.gov