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LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction

NCT07466641 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2026-05-11

No results posted yet for this study

Summary

This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction. Participants will be randomly assigned to one of three groups: piezocision, LLLT, or a control group (no adjunctive procedure). The study will assess the impact of these interventions on the rate of tooth movement, the type of tooth movement, and patient experience.

Conditions

  • Bimaxillary Protrusion
  • Malocclusion, Angle Class II, Division 1
  • Class I Malocclusion

Interventions

PROCEDURE

Low Level Laser Therapy

On both right and left sides, LLLT will be performed at the beginning of canine retraction, after 3, 7, 14 days, and then every 14 days for a total four-month period.

PROCEDURE

Piezocision

On both right and left sides, a minimally invasive flapless piezocision procedure will be performed each month from the beginning of the canine retraction for a total four-month period.

Sponsors & Collaborators

  • Al-Azhar University

    collaborator OTHER

  • Hesham Nabil Ali Al-Qamhawy

    lead OTHER

Principal Investigators

  • Farouk A Hussein, Professor · Professor in Orthodontics; Faculty of Dental Medicine, Boys, Cairo; Al-Azhar University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-04-01
Primary Completion
2027-02-28
Completion
2027-06-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07466641 on ClinicalTrials.gov