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Preventing Early Childhood Caries With a Silver Diamine Fluoride Gel

NCT07455604 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1500

Last updated 2026-03-06

No results posted yet for this study

Summary

The objective is to compare the efficacy of SDF gel with that of NaF varnish in preventing carious lesions in preschool children when applied at half-yearly intervals over a 24-month period.

Conditions

  • Early Childhood Caries (ECC)

Interventions

DRUG

Silver diamine fluoride gel

Application of 38% SDF gel every 6 months over 24 months

DRUG

Sodium Fluoride varnish

Application of 5% NaF varnish every 6 months over 24 months

Sponsors & Collaborators

  • The University of Hong Kong

    lead OTHER

Principal Investigators

  • Chun Hung Chu · The University of Hong Kong

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
3 Years
Max Age
5 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-01
Primary Completion
2028-08-31
Completion
2028-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07455604 on ClinicalTrials.gov