Smartphone-based Telerehabilitation Versus Home-based Inspiratory Muscle Training After Lung Resection in High-risk Patients

Summary

The goal of this clinical trial is to learn whether smartphone-based telerehabilitation for inspiratory muscle training (IMT) can improve postoperative recovery in high-risk adult patients after lung resection. Eligible participants are adults aged 19 years or older who underwent lung resection and met at least one high-risk criterion: preoperative forced expiratory volume in 1 second (FEV1) or diffusing capacity of the lung for carbon monoxide (DLCO) of 70% predicted or less, or age 65 years or older. The main questions it aims to answer are:

Does smartphone-based telerehabilitation for IMT improve functional exercise capacity, as measured by the 6-minute walk test (6MWT)? Is smartphone-based telerehabilitation for IMT feasible and safe in this patient population?

Researchers will compare smartphone-based telerehabilitation IMT with unsupervised home-based IMT to see whether remote supervision provides additional benefit after lung resection.

Participants will:

be randomized to either smartphone-based telerehabilitation IMT or unsupervised home-based IMT perform IMT 5 days per week for 6 weeks, starting at 20% of postoperative maximal inspiratory pressure (MIP) with progression according to tolerance complete outcome assessments at postoperative weeks 2-4, 8-10, and 14-16, including the 6MWT, pulmonary function tests (FVC, FEV1, MIP, and peak expiratory flow), handgrip strength, body composition, patient-reported outcomes, and cardiopulmonary exercise testing at final follow-up

Conditions

• Pulmonary Disease
• Lung Cancer (Diagnosis)

Interventions

BEHAVIORAL

Smartphone-based telerehabilitation IMT

Home-based inspiratory muscle training performed for 6 weeks (5 days per week, 10 repetitions × 10 sets per day), starting at 20% of postoperative maximal inspiratory pressure (MIP) with progression according to tolerance and symptoms. Participants receive smartphone-based telerehabilitation support through a mobile messenger application, including adherence checks, symptom monitoring, therapist feedback, and remote support for training progression.

BEHAVIORAL

Unsupervised home-based IMT

Home-based inspiratory muscle training performed for 6 weeks (5 days per week, 10 repetitions × 10 sets per day), starting at 20% of postoperative maximal inspiratory pressure (MIP) with progression according to tolerance. After a one-time instruction session, participants continue the training independently without additional remote monitoring.

Sponsors & Collaborators

• National Research Foundation of Korea

  collaborator OTHER

• Pusan National University Hospital

  lead OTHER

Principal Investigators

• Sanghun Kim, MD,PhD · Pusan National University Hospital

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

19 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-08-13

Primary Completion

2025-12-29

Completion

2025-12-29

Countries

• South Korea

Study Locations