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Blue Light for Donor Site Healing in Burn Patients

NCT07453927 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2026-04-06

No results posted yet for this study

Summary

The goal of this clinical trial is to learn whether blue light (BL) photobiomodulation can improve the healing of donor site (DS) wounds in patients with burn injuries who are treated surgically. This study will investigate whether adding BL therapy to the usual treatment can improve healing and patient outcomes in adult patients with intermediate and deep burns.

The main questions it aims to answer are:

* Does the use of BL therapy combined with standard treatment reduce the healing time of DS compared with standard treatment alone?
* Does BL therapy improve wound conditions, reduce pain, and decrease signs of infection during the healing process?
* Is BL therapy safe and well tolerated when applied to DS?
* Does the treatment improve the long-term quality of the scar after healing?

Researchers will compare DS areas treated with standard care alone to DS areas treated with standard care plus BL therapy to see whether BL improves healing outcomes. Each participant will serve as their own comparison: two different DS areas on the same patient will receive the two different treatments.

Participants will:

* Receive the standard treatment for DS, which includes routine wound care and dressing
* Receive BL therapy on one DS area in addition to the standard treatment, while another DS area will receive standard treatment alone
* Attend regular clinical evaluations where clinicians will assess wound healing and the condition of the wound bed
* Report their pain levels using a simple numeric scale during the healing period
* Undergo skin swabs to detect possible signs of infection
* Be monitored for any local side effects, such as redness, burning sensation, warmth, itching, or skin irritation related to the light treatment

After the DS have completely healed, participants will return for follow-up visits at 1 month and 3 months. During these visits, researchers will evaluate the quality of the scars and monitor for any late side effects.

Conditions

  • Donor Site Complication
  • Burn
  • Photobiomodulation Therapy
  • Blue Light

Interventions

DEVICE

Photobiomodulation with blue light

The BL will be applied to the entire DS for 60 seconds, with one session per week, for a total of 3-4 weeks depending on the healing process.

Sponsors & Collaborators

  • AUSL Romagna Rimini

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-29
Primary Completion
2026-07-31
Completion
2026-09-28

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07453927 on ClinicalTrials.gov