Research on Real-time Proton Therapy Guidance Through Monitoring Proton Range Using All-digital PET
NCT07450560 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2026-03-10
Summary
The energy transport process of proton beams after entering biological tissue is observed online via proton knife fully digital PET. The dynamic changes of the delivered dose and action range of proton beams in biological tissue are analyzed, the proton dose distribution is reconstructed, and the energy and position of the targeted ablation by proton beams are determined, so as to realize in-beam online PET monitoring for proton therapy.
Conditions
Interventions
- RADIATION
-
proton therapy
proton therapy
Sponsors & Collaborators
-
Shuanghu Yuan
lead OTHER
Principal Investigators
-
Xiaojing Wang, MD · Anhui Provincial Cancer Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-02-01
- Primary Completion
- 2028-12-31
- Completion
- 2028-12-31
Countries
- China
Study Locations
More Related Trials
-
Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
NCT02040610 ·Status: RECRUITING ·Phase: NA
-
A Study of the Value of Hybrid PET/MR and PET/CT in Prostate Cancer
NCT03756077 ·Status: UNKNOWN
-
PET-CT/MRI in the Radiotherapy for Prostate Cancer
NCT02816840 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
177Lu-P17-087/177Lu-P17-088 in Patients With Metastatic Castration-resistant Prostate Cancer
NCT05603559 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
68Ga-NOTA-BBN-RGD PET/CT in Prostate Cancer Patients
NCT02747290 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Proton Beam Radiation Therapy for Early Stage Adenocarcinoma of the Prostate
NCT00585962 ·Status: COMPLETED ·Phase: PHASE2
-
Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer
NCT04597411 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer
NCT03403595 ·Status: UNKNOWN ·Phase: PHASE1
-
68Ga-P16-093 and 68Ga-PSMA-617 PET/CT Imaging in the Same Group of Prostate Cancer Patients
NCT04796467 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
12 Fractions Carbon Ion Radiotherapy for Localized Prostate Cancer
NCT04724577 ·Status: UNKNOWN ·Phase: NA
-
68Ga-NOTA-RM26 PET/CT in Prostate Cancer Patients
NCT03164837 ·Status: UNKNOWN ·Phase: PHASE1
-
Acute Toxicity After Moderate Hypo-fractionated Intensity Modulated Radiotherapy IMRT or Prostate Cancer
NCT05265364 ·Status: ACTIVE_NOT_RECRUITING
-
High-intensity Focused Ultrasound Study
NCT03927924 ·Status: TERMINATED ·Phase: NA
-
Research on the Application of 68Ga-PSMA-CYC PET Imaging in the Diagnosis, Staging, and Restaging of Prostate Cancer
NCT07056790 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Is it Feasible to Use Data Obtained Through a Three-Dimensional Reconstructed Image to Assist in Prostate Targeted Biopsy?
NCT07296510 ·Status: COMPLETED
-
Intensity Modulated Radiation Therapy for Prostate Cancer
NCT00214422 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
PSMA Specific [68Ga]-P137 Peptide Probe for PET Imaging in Prostate Cancer
NCT04560725 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Diagnostic Application of PSMAPET/MR in Patients Undergoing Secondary Prostate Puncture
NCT06901492 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Molecular PET/MR Imaging in Vivo Validation of Biomarker for Human Prostate Cancer
NCT03451812 ·Status: UNKNOWN
-
Phase I/II Clinical Study of HRS-1738 for the Diagnosis of Prostate Cancer Patients
NCT07056439 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase II Clinical Study of Stereotactic Radiation Therapy in Patients With High-risk Prostate Cancer
NCT05430737 ·Status: UNKNOWN ·Phase: NA
-
PSMA-PET/MRI Unfavorable-Risk Target Volume Pilot Study
NCT04176497 ·Status: TERMINATED ·Phase: PHASE2
-
A Multi-centre Trial on Targeted Microwave Ablation (TMA) for Localized Prostate Cancer
NCT06262633 ·Status: RECRUITING ·Phase: NA
-
High-intensity Focused Ultrasound Combined With Novel Hormone Therapy in Advanced Prostate Cancer
NCT07126093 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
[68Ga]Ga-P17-079 in the Diagnosis and Treatment of Metastatic Prostate Cancer
NCT06864572 ·Status: ENROLLING_BY_INVITATION ·Phase: EARLY_PHASE1