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Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome

NCT07446634 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2026-03-03

No results posted yet for this study

Summary

This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard treatments such as Continous Positive Airway pressure treatment. The participants are followed over time to see whether the surgery improves sleep apnea symptoms, daytime sleepiness, and airway size, and whether these improvements last. Advanced three-dimensional imaging and airflow analysis are used to better understand how the surgery changes the airway and breathing. The goal is to evaluate the long-term effectiveness and safety of this surgical treatment.

Conditions

  • Sleep Apnea, Obstructive

Interventions

PROCEDURE

Maxillomandibular advancement surgery with counterclockwise rotation

Maxillary advancement by LeFort I osteotomy and mandibular advancement by bilateral sagittal split osteotomy

Sponsors & Collaborators

  • Jani Talvilahti

    lead OTHER

Principal Investigators

  • Andreas Thor, Professor · Department of Surgical Sciences, Oral and Maxillofacial Surgery, Uppsala University, Uppsala, Sweden.

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-06
Primary Completion
2031-06-30
Completion
2032-06-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07446634 on ClinicalTrials.gov