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MRI-Based Prediction of Dienogest Response in Endometriosis

NCT07446608 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2026-03-03

No results posted yet for this study

Summary

The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary.

The main questions this study aims to answer are:

* Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment.
* Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy.

Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.

Conditions

  • Endometriosis, Ovarian

Sponsors & Collaborators

  • Chungnam National University Sejong Hospital

    lead OTHER

Eligibility

Min Age
19 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-10-14
Primary Completion
2027-03-31
Completion
2027-03-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07446608 on ClinicalTrials.gov