Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock
NCT07444073 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 440
Last updated 2026-03-02
Summary
This study examines whether routine treatment with semaglutide or tirzepatide, prescribed with lifestyle coaching in a real-world weight-management program, is associated with changes in biological age measured by the LinAge2 clinical aging clock over 6 months.
Conditions
- Aging
- Obesity & Overweight
Interventions
- OTHER
-
Not applicable. This is an observational study.
Not applicable. This is an observational study.
Sponsors & Collaborators
-
T3 Health PTE LTD
collaborator UNKNOWN -
National University of Singapore
lead OTHER
Principal Investigators
-
Jan Gruber, PhD · National University of Singapore
Eligibility
- Min Age
- 40 Years
- Max Age
- 89 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-02-02
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Singapore
Study Locations
More Related Trials
-
Semaglutide Use in Elderly Obese Patients
NCT05302596 ·Status: COMPLETED ·Phase: PHASE2
-
Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic Surgery
NCT07374445 ·Status: COMPLETED ·Phase: PHASE4
-
Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic Outcomes
NCT07424430 ·Status: NOT_YET_RECRUITING
-
Semaglutide's Weight Loss Effects in Obesity
NCT06825793 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range
NCT06041217 ·Status: COMPLETED ·Phase: PHASE3
-
Research Study of How Well Semaglutide Works in People Living With Overweight or Obesity.
NCT04251156 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss
NCT04660643 ·Status: COMPLETED ·Phase: PHASE3
-
Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity in the Real World
NCT06874751 ·Status: COMPLETED
-
Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults
NCT06811324 ·Status: RECRUITING ·Phase: PHASE2
-
Tirzepatide and Muscle Outcomes in Obesity
NCT07373834 ·Status: RECRUITING ·Phase: NA
-
Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle Program
NCT03611582 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subjects
NCT06738979 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
The Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight Patients
NCT04605861 ·Status: COMPLETED ·Phase: PHASE3
-
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
NCT06143956 ·Status: RECRUITING ·Phase: PHASE2
-
Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548987 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
NCT04657016 ·Status: COMPLETED ·Phase: PHASE3
-
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
NCT07091500 ·Status: RECRUITING ·Phase: NA
-
Tirzepatide vs Liraglutide in Bone
NCT07094568 ·Status: RECRUITING
-
Therapeutic Effects and Effects on Body Fat of GLP-1 Receptor Agonists in Patients With Type 2 Diabetes for 1-4 Years
NCT05990374 ·Status: UNKNOWN ·Phase: NA
-
A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes
NCT06603571 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
NCT05933499 ·Status: RECRUITING ·Phase: PHASE2
-
STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or Obesity
NCT03811574 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight
NCT04657003 ·Status: COMPLETED ·Phase: PHASE3
-
Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity
NCT04074161 ·Status: COMPLETED ·Phase: PHASE3
-
Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.
NCT07411378 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2