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Evaluation of Pine Bark Extract for Anti-fatigue Ergogenic Properties

NCT07440394 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2026-02-27

No results posted yet for this study

Summary

This research proposal aims to elucidate the physiological responses to pine bark extract supplementation during a single bout of high-intensity cycling exercise at 70% VO₂max and the subsequent recovery phase. Specifically, the study seeks to investigate the underlying mechanisms by which pine bark extract modulates exercise-induced fatigue and metabolic fitness, and to determine whether such supplementation may enhance endurance performance in the post-recovery period.

Conditions

  • Healthy

Interventions

OTHER

Placebo (Placebo trial)

The Placebo capsule supplement was taken for 4 days (3 capsules per day)

OTHER

PBE (PBE trial)

The PBE capsule supplement was taken for 4 days, with a daily dosage of 300 mg of PBE (equivalent to 3 capsules per day, each containing 100 mg of PBE).

Sponsors & Collaborators

  • National Science and Technology Council, Taiwan

    collaborator OTHER_GOV

  • China Medical University, Taiwan

    collaborator OTHER

  • China Medical University Hospital

    lead OTHER

Principal Investigators

  • Jung-Piao Tsao · China Medical University, China

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-21
Primary Completion
2023-10-01
Completion
2023-12-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07440394 on ClinicalTrials.gov