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Predictors of Decompensation, Acute-on-chronic Liver Failure and Mortality in Liver Cirrhosis

NCT07438288 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2200

Last updated 2026-02-27

No results posted yet for this study

Summary

The purpose of this study is to identify factors that predict the development of decompensation, acute-on-chronic liver failure (ACLF) and death in patients with liver cirrhosis. Clinical data will be retrieved from existing hospital records. This information may help doctors to identify patients with cirrhosis who are at risk of deterioration earlier (before they develop complications) and to develop effective treatment strategies to prevent or delay these complications.

This study is designed as a prospective, non-interventional, observational study. This means that if you agree to participate in the study, you will not be required to undergo any additional hospital visits, tests, procedures or interventions other than the usual standard-of-care management that your doctor will provide. If you consent to participate in this study, you will be providing the study investigators permission to review and analyse your clinical data from the hospital clinical records. Your data will be collected throughout the course of your disease until liver transplantation or death.

Conditions

  • Cirrhosis and Chronic Liver Disease

Interventions

OTHER

Observation

Patients with liver cirrhosis will be observed to monitor for death

Sponsors & Collaborators

  • Singapore General Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-12
Primary Completion
2027-08-12
Completion
2032-08-12

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07438288 on ClinicalTrials.gov