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Video vs. Direct Laryngoscopy for Less Invasive Surfactant Administration

NCT07426016 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-06-01

No results posted yet for this study

Summary

Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs. The goal of the study is to compare the use of video-based visualization to direct visualization during a procedure called less invasive surfactant administration (LISA). The main questions the study aims to answer are: 1) does one method of visualization have a increased rate of giving the medicine successfully on the first attempt? 2) what benefits are there of each method?

Conditions

  • Respiratory Distress Syndrome (Neonatal)
  • Surfactant Deficiency Syndrome Neonatal

Interventions

PROCEDURE

Video Laryngoscopy

Video Laryngoscopy will be used to visualize the vocal cords and place the LISA catheter

PROCEDURE

Direct Laryngoscopy

Direct Laryngoscopy will be used to visualize the vocal cords and place the LISA catheter

Sponsors & Collaborators

  • University of Texas Southwestern Medical Center

    lead OTHER

Principal Investigators

  • Chokshi, MD · UT Southwestern

  • Shalini Ramachandran, MD · UT Southwestern

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
0 Hours
Max Age
3 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-30
Primary Completion
2028-06-30
Completion
2028-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07426016 on ClinicalTrials.gov