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Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair

NCT07422441 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-02-20

No results posted yet for this study

Summary

People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.

Conditions

  • Hernia, Ventral
  • Hernia Incisional
  • Postoperative Complications
  • Respiratory Insufficiency

Interventions

OTHER

Compliance-Guided Abdominal Wall Closure Decision Strategy

A predefined intraoperative decision strategy that uses standardized measurements of static respiratory system compliance (Cstat) during abdominal wall closure to support selection of closure technique, with a predefined physiological tolerance threshold based on the baseline measurement.

Sponsors & Collaborators

  • Medical University of Gdansk

    collaborator OTHER

  • Swissmed Hospital

    lead OTHER

Principal Investigators

  • Irmina Anna Śmietański, MD, PhD · Śmietański Hernia Center, LUX MED Hospital in Gdańsk

  • Maciej Śmietański, Prof. · Śmietański Hernia Center, LUX MED Hospital in Gdańsk

  • Mateusz Zamkowski, MD, PhD · Śmietański Hernia Center, LUX MED Hospital in Gdańsk

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-20
Primary Completion
2026-08-01
Completion
2026-11-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07422441 on ClinicalTrials.gov