Comparison of Intralesional Triamcinolone Acetonide Treatment With Intralesional Verapamil Hydrochloride in Keloids
NCT07420166 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2026-02-19
Summary
The paucity of local literature regarding the comparison of intralesional verapamil with intralesional triamcinolone acetonide led this study to be carried out with the objective of comparing the clinical effectiveness of intralesional triamcinolone acetonide and intralesional verapamil hydrochloride in patients with keloids.
Conditions
- Keloid
Interventions
- DRUG
-
Triamcinolone Acetonide
Patients received intralesional triamcinolone acetonide (20 mg/ml) at a volume not exceeding 1.5 cc per session every three weeks, for a maximum of eight sessions or until complete scar flattening. Each injection session was preceded by 20 seconds of cryotherapy using cryospray applied at a distance of one centimeter from the lesion.
- DRUG
-
Verapamil Hydrochloride
Patients were managed with intralesional verapamil hydrochloride (2.5 mg/ml) at a volume not exceeding 1.5 cc per session every three weeks, for a maximum of eight sessions or until complete scar flattening. Each injection session was preceded by 20 seconds of cryotherapy using cryospray applied at a distance of one centimeter from the lesion.
Sponsors & Collaborators
-
Muhammad Aamir Latif
lead OTHER
Principal Investigators
-
Bakhtawar · Bahawal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur
-
Salman Ashraf, FCPS · Bahawal Victoria Hospital/Quaid-e-Azam Medical College, Bahawalpur
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-01-01
- Primary Completion
- 2025-06-30
- Completion
- 2025-06-30
Countries
- Pakistan
Study Locations
More Related Trials
-
The Effectiveness of Intralesional Botulinum Toxin A and Triamcinolone Acetonide Injections in Keloid Treatment
NCT06814288 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Comparison of the Efficacy of Different Steroids in the Treatment of Abnormal Scars (Keloids, Hypertrophic Scars)
NCT04593706 ·Status: UNKNOWN ·Phase: NA
-
Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of Keloids
NCT04710719 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids
NCT04391621 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparative Study Between Intralesional Corticosteroid Injection Alone and Combined Intralesional Corticosteroid Injection With Either Long-pluse Nd YAG or Erbium Yag for Treating Hypertrophic or Keloid Scars
NCT07263100 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Fractional CO2 Laser Combined With Intralesional Insulin, Botulinum Toxin or Triamcinolone Acetonide in the Treatment of Keloid: A Clinical, Dermoscopic and Immunohistochemical Study.
NCT06230146 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Topical Cryotherapy and Keloid/Hypertrophic Scars
NCT07336368 ·Status: RECRUITING ·Phase: PHASE3
-
Comparison of Recurrence Rate of Keloid After Excision Between Intra-operative Steroid Injection and Steroid With Platelet-rich Plasma Injection Combination Therapy
NCT06965088 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Prevention of Hypertrophic Scars or Keloids
NCT00849004 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial
NCT05887804 ·Status: COMPLETED ·Phase: PHASE4
-
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
NCT05939817 ·Status: COMPLETED ·Phase: PHASE4
-
Photobiomodulation and the Intralesional Administration of Corticoid in the Keloid Surgery.
NCT04824612 ·Status: COMPLETED ·Phase: NA
-
Implantation of Mesenchymal Stem Cell, Conditioned Medium, or Triamcinolone Acetonide for Keloid
NCT04326959 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Calcium Electroporation for the Treatment of Keloids
NCT01941914 ·Status: COMPLETED ·Phase: PHASE1
-
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
NCT04597060 ·Status: UNKNOWN ·Phase: NA
-
Study of Psycho-Social Impact of Keloid
NCT01478243 ·Status: TERMINATED
-
A Post Market Study Evaluating the Safety, Device Perfomance and Possible Emergent Risks of Celotres in Preventing Recurrence in Keloid Lesions Treated Adjunctive to Surgical Excision
NCT01706861 ·Status: COMPLETED ·Phase: NA
-
Initial Assessment of a Topical Cadexomer Iodine Gel Efficacy on Keloid Scar Revision
NCT03876548 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
A Randomized Comparative Study Evaluating the Tolerability and Efficacy of Two Topical Therapies for the Treatment of Keloids and Hypertrophic Scars
NCT00754247 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Effectiveness and Safety of RXI-109 on the Outcome of Keloid Excision Surgery in Healthy Adults
NCT02079168 ·Status: COMPLETED ·Phase: PHASE2
-
Observational Study of Keloids Scars Treated by Shaving and Cryosurgery
NCT02886091 ·Status: UNKNOWN
-
Intralesional Treatment of Keloids
NCT06729840 ·Status: RECRUITING ·Phase: PHASE3
-
Comparison of Cosmetic and Functional Outcome of Silicone Sheeting and Micro-needling on Hypertrophic Scars
NCT05108272 ·Status: UNKNOWN ·Phase: NA
-
Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars
NCT02063243 ·Status: COMPLETED ·Phase: NA
-
Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars
NCT01978301 ·Status: TERMINATED ·Phase: PHASE1