MedTrace Logo

Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial

NCT07413055 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 138

Last updated 2026-03-30

No results posted yet for this study

Summary

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site.

Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded.

Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores.

The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.

Conditions

  • Postoperative Pain

Interventions

DRUG

Dexamethasone 4 Mg/mL Injectable Solution

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule

DRUG

Dexamethasone 8Mg Solution for Injection

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule

DRUG

Saline (NaCl 0,9 %) (placebo)

Syringe will be concealed. Submucosal injection will be adjacent to the surgical site in the buccal vestibule

Sponsors & Collaborators

  • Oman Ministry of Health

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-25
Primary Completion
2026-11-15
Completion
2026-12-01

Countries

  • Oman

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07413055 on ClinicalTrials.gov