MedTrace Logo

Supersaturated Hydrogen-Rich Water for Outpatients With Persistent Excess Weight

NCT07410065 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-02-13

No results posted yet for this study

Summary

The Supersaturated Hydrogen-Rich Water for Outpatients with Persistent Excess Weight (HOPE) study is a Phase III, multicenter, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of daily consumption of supersaturated hydrogen-rich water in adults with persistent excess body weight. The trial investigates whether sustained exposure to molecular hydrogen can favorably influence body composition and key metabolic outcomes compared with a placebo water lacking dissolved hydrogen. By enrolling outpatients across multiple centers and applying rigorous blinding and randomization procedures, HOPE aims to generate high-quality clinical evidence on the potential role of hydrogen-rich water as a non-pharmacological, adjunctive strategy for weight management and metabolic health.

Conditions

Interventions

DIETARY_SUPPLEMENT

Hydrogen-rich water

Hydrogen-rich water (1.0 L per day)

DIETARY_SUPPLEMENT

Control

Hydrogen-free water (1.0 L per day)

Sponsors & Collaborators

  • Center for Health Sciences, Serbia

    lead OTHER

Principal Investigators

  • Nikola Todorovic, PhD · Center for Mitochondrial Medicine

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-04-15
Primary Completion
2027-01-15
Completion
2027-02-15

Countries

  • Serbia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07410065 on ClinicalTrials.gov