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MRI-tDCS Criticism Study

NCT07406464 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 47

Last updated 2026-02-12

No results posted yet for this study

Summary

This experimental study investigated how MRI-compatible transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex (DLPFC) modulates neural and cognitive responses to social criticism in healthy volunteers.

Participants underwent two MRI sessions - one with active and one with sham stimulation - in a randomized, double-blind, cross-over design.

During stimulation, they completed resting-state and task-based fMRI scans including exposure to critical, neutral, and praising auditory comments, followed by behavioral and self-report measures of rumination, mood, and implicit self-esteem.

Conditions

  • Healthy Participant Study

Interventions

DEVICE

tDCS

Participants are randomized to receive either active or sham tDCS during MRI scanning. Neuroimaging and behavioral outcomes are used to assess the effects of stimulation on emotion-related brain networks.

Sponsors & Collaborators

  • University Ghent

    collaborator OTHER

  • Universitair Ziekenhuis Brussel

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-07-09
Primary Completion
2014-03-02
Completion
2014-03-02

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07406464 on ClinicalTrials.gov