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The Effect of Dapagliflozin on Myocardial Strain in Patients With Acute Heart Failure

NCT07403955 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 188

Last updated 2026-03-24

No results posted yet for this study

Summary

The goal of this clinical trial is to assess the impact of dapagliflozin on myocardial strain in patients with acute heart failure using speckle tracking echocardiography (STE).

The main questions it aims to answer are:

* Does dapagliflozin improve left ventricular remodeling as well as cardiac systolic and diastolic function?
* Can STE more accurately assess the impact of dapagliflozin on myocardial strain in patients with acute heart failure? Researchers will compare patients receiving oral dapagliflozin to those not receiving it to see if dapagliflozin works to improve left ventricular remodeling as well as cardiac systolic and diastolic function.

Participants will:

* Take dapagliflozin or not every day for 1 month
* Take dapagliflozin for the next 2 months
* Visit the clinic at Month 1 and Month 3 for checkups and tests

Conditions

  • Congestive Heart Failure Acute

Interventions

DRUG

Dapagliflozin 10mg Tab

Compared with the control group, dapagliflozin is started within the first month after the onset of acute heart failure.

Sponsors & Collaborators

  • Qilu Hospital of Shandong University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-28
Primary Completion
2027-12-31
Completion
2028-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07403955 on ClinicalTrials.gov