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Comparison of IVF Outcomes Between PPOS and Antagonist Protocols in Women With PCOS

NCT07394530 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2026-02-11

No results posted yet for this study

Summary

This study aims to compare the outcomes of two ovarian stimulation protocols used in in vitro fertilization (IVF): the progestin-primed ovarian stimulation (PPOS) protocol and the GnRH antagonist protocol.

Conditions

  • Polycystic Ovary Syndrome (PCOS)
  • Female Infertility

Interventions

DRUG

Progestin-Primed Ovarian Stimulation (PPOS)

Ovarian stimulation using a progestin-primed ovarian stimulation (PPOS) protocol, including gonadotropins combined with oral progestin for pituitary suppression during in vitro fertilization treatment.

DRUG

GnRH Antagonist Protocol

Ovarian stimulation using a gonadotropin-releasing hormone (GnRH) antagonist protocol for pituitary suppression during in vitro fertilization treatment.

Sponsors & Collaborators

  • Hanoi General Hospital (Vietnam)

    lead OTHER

Principal Investigators

  • Phuong Duy Nguyen, MD, MS · Hanoi General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-20
Primary Completion
2027-06-30
Completion
2028-06-30

Countries

  • Vietnam

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07394530 on ClinicalTrials.gov