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Comparison of Effect of Dexmedetomidine and Midazolam on Emergence Agitation

NCT07392983 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 146

Last updated 2026-02-06

No results posted yet for this study

Summary

Since the frequency of emergence agitation (EA) is relatively high in children while undergoing nasal surgery, and there is not much data available in Pakistan regarding EA in adults undergoing functional endoscopic sinus surgery (FESS). Hence there is a need to conduct this study in the local population to see the effect of dexmedetomidine and midazolam on EA. Therefore, the current study was initiated, aiming to compare the effect of dexmedetomidine and midazolam on EA in patients undergoing FESS.

Conditions

  • Emergence Agitation

Interventions

DRUG

Dexmedetomidine

Patients were given dexmedetomidine injection with a loading dose of 1 µg/kg in 10 minute prior to the procedure.

DRUG

Midazolam

Patients received midazolam with a loading dose of 0.02 mg/kg in 10 min prior to the procedure.

Sponsors & Collaborators

  • Muhammad Aamir Latif

    lead OTHER

Principal Investigators

  • Madiha Ashraf · Bahawal Victoria Hospital/Quid-e-Azam Medical College, Bahawalpur

  • Ambreen Khan, FCPS · Bahawal Victoria Hospital/Quid-e-Azam Medical College, Bahawalpur

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
16 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-01
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07392983 on ClinicalTrials.gov