Postoperative Cognitive Dysfunction in Elderly and it's Relation With Sleep Disorders and Melanin Concentrating Hormone
NCT07392840 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2026-02-10
Summary
The aim of this study is to explore the relationship between preoperative sleep disorders, melanin-concentrating hormone (MCH), and delayed neurocognitive recovery early after surgery in older adult patients undergoing spinal anesthesia.
Conditions
- Postoperative Cognitive Dysfunction
Sponsors & Collaborators
-
Minia University
lead OTHER
Principal Investigators
-
Mohamed Mostafa Ali, MD · El-minya University Hospital
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-02-01
- Primary Completion
- 2027-02-01
- Completion
- 2027-04-01
More Related Trials
-
Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium
NCT03498560 ·Status: COMPLETED
-
Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
NCT04267328 ·Status: COMPLETED
-
Correlation Between Postoperative Cognitive-related Adverse Reactions and Brain Metabolomic Characteristics in Elderly Patients
NCT05555693 ·Status: RECRUITING
-
Post-operative Cognitive Dysfunction and the Change of Regional Cerebral Oxygen Saturation in Elderly Patients Undergoing Spinal Surgery
NCT01839227 ·Status: COMPLETED ·Phase: NA
-
Relationship Between Perioperative Sleep Disturbance and Postoperative Delirium
NCT05457387 ·Status: COMPLETED
-
Clinical Outcomes in Elderly Patients With Preoperative Cognitive Dysfunction
NCT03143595 ·Status: UNKNOWN
-
Preoperative Sleep Quality and Postoperative Delirium
NCT06273358 ·Status: COMPLETED
-
Sleep Longitudinal Exploration of the Experience of Patients
NCT06888427 ·Status: RECRUITING
-
Electroencephalogram Characteristics of Surgical Anesthetized Patients and Postoperative Dilirium
NCT06394778 ·Status: ENROLLING_BY_INVITATION
-
General Versus Regional Anesthesia and Postoperative Sleep Quality
NCT03843645 ·Status: UNKNOWN ·Phase: NA
-
Pre-operative Neurocognitive Disorder and Low Near-infrared Spectrometry is Associated With Postoperative Delirium
NCT03171766 ·Status: UNKNOWN
-
Dexamethasone for the Prevention of Postoperative Cognitive Dysfunction
NCT01332812 ·Status: COMPLETED ·Phase: PHASE4
-
Cognitive Trajectories After Surgery, a Clinical, Observational Feasibility Study
NCT05564195 ·Status: COMPLETED
-
Discovery for Biomarkers and Risk Factors for Postoperative Delirium in Elderly Patients With Spine Surgery
NCT04120272 ·Status: UNKNOWN
-
Neurocognitive Function After Regional and General Anesthesia (245_14 B)
NCT02505815 ·Status: COMPLETED
-
Cognitive Impairment Following Elective Spine Surgery
NCT03486288 ·Status: TERMINATED
-
Biomarkers and Risk Factors for Perioperative Neurocognitive Dysfunction in Elderly Patients
NCT06044207 ·Status: RECRUITING
-
Does Preoperative Sleep Quality Affect the Postoperative Emergence Delirium in Children Undergoing Strabismus Surgery
NCT03332407 ·Status: COMPLETED
-
Post Operative Cognitive Dysfunction
NCT03067259 ·Status: COMPLETED ·Phase: NA
-
A Prospective Cohort Study of Perioperative Covert Stroke and Postoperative Cognitive Dysfunction
NCT03081429 ·Status: COMPLETED
-
Role of REM Sleep Alterations in Post Operative Delirium After Cardiac Surgery
NCT02801318 ·Status: UNKNOWN ·Phase: NA
-
Postoperative Neurocognitive Disorders
NCT04244162 ·Status: COMPLETED
-
The Effect of Circadian Clock System on Perioperative Cognitive Function of Elderly Patients
NCT04194866 ·Status: UNKNOWN ·Phase: NA
-
"Effects of Fluid Status and Regional Cerebral Oxygenation on Postoperative Cognitive Dysfunction in Patients Undergoing Lower Extremity Surgery Under General and Spinal Anesthesia."
NCT07302061 ·Status: ACTIVE_NOT_RECRUITING
-
Optimizing Postoperative Cognition the Elderly
NCT02650687 ·Status: COMPLETED