Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection
NCT07386626 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 118
Last updated 2026-04-08
Summary
Combining tegileridine PCIA with ICNB targeting peripheral nerves, may constitute an ideal analgesic model with complementary advantages. Thus potentially achieving the analgesic goal of "early pain relief, stable throughout the process, and rapid recovery," and may have a positive impact on reducing CPSP.
Conditions
- Lobectomy
Interventions
- DRUG
-
Tegileridine
Administer 0.015 mg/kg (maximum 1mg) of tegileridine intravenously 40 minutes before the end of surgery, followed by the connection of a tegileridine patient-controlled intravenous analgesia (PCIA)
- PROCEDURE
-
Intercostal Nerve Block
Before closing the chest, the thoracic surgeon injected 3mL of 0.4% ropivacaine into the 4th, 5th, 6th and 7th intercostal spaces through thoracoscopy for intercostal nerve block.
- DRUG
-
Sufentanil
Administer 0.15 μg/kg (maximum 10 μg) of sufentanil intravenously 40 minutes before the end of surgery, followed by the connection of a sufentanil patient-controlled intravenous analgesia (PCIA)
Sponsors & Collaborators
-
Tongji Hospital
lead OTHER
Principal Investigators
-
aihua Du, Dr. · Tongji Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-18
- Primary Completion
- 2026-12-31
- Completion
- 2027-01-31
Countries
- China
Study Locations
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