Evaluation of Postoperative Adjuvant Chemotherapy Efficacy for Bladder Cancer Based on Organoid Technology.

Summary

To evaluate the clinical efficacy of using tumor organoid drug sensitivity experiments to guide postoperative adjuvant chemotherapy in patients with muscle-invasive bladder cancer, and to assess the application value of tumor organoid drug sensitivity experiments in guiding individualized postoperative adjuvant chemotherapy for muscle-invasive bladder cancer.

Conditions

• Bladder Cancer

Interventions

OTHER

Organoid culture

Organoid culture of tumor tissue obtained during patient surgery

Sponsors & Collaborators

• The Second Hospital of Shandong University

  collaborator OTHER

• Qianfoshan Hospital

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Shandong Province Third hospital

  collaborator OTHER

• Taian City Central Hospital

  collaborator OTHER

• Weifang People's Hospital

  collaborator OTHER

• Binzhou Medical University

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  collaborator OTHER

• Jining First People's Hospital

  collaborator OTHER

• Liaocheng People's Hospital

  collaborator OTHER

• Linyi People's Hospital

  collaborator OTHER

• Yantai Yuhuangding Hospital

  collaborator OTHER

• Zibo Central Hospital

  collaborator OTHER_GOV

• Dezhou Hospital Qilu Hospital of Shandong University

  collaborator OTHER

• Zaozhuang Municipal Hospital

  collaborator OTHER

• Qilu Hospital of Shandong University (Qingdao)

  collaborator OTHER

• Qilu Hospital of Shandong University

  lead OTHER

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-01-01

Primary Completion

2030-12-31

Completion

2030-12-31

Countries

• China

Study Locations